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Prevention of arterial thrombosis and venous thrombosis, treatment drugs and methods, the two are different

Time:2023-02-01 09:57:26 source:psychiatricethics.com author:Relax Read:358次
Prevention of arterial thrombosis and venous thrombosis, treatment drugs and methods, the two are different

A friend told Hua Zi that he heard that in the prevention of cardiovascular and cerebrovascular diseases, there are two treatment methods, anti-platelet therapy and anti-coagulation therapy, both of which can prevent thrombosis. What is the difference? Hua Zi said that there are two types of thrombus in the human body. One is formed in the arterial system, which can cause cardiovascular and cerebrovascular diseases such as cerebral infarction and myocardial infarction; the other is formed in the venous system, which mainly causes pulmonary embolism and may also cause cerebral infarction. infarction. These are both potentially life-threatening diseases, and the two conditions require different medications for prevention, requiring antiplatelet therapy and anticoagulant therapy, respectively.

First, antiplatelet therapy

The formation of arterial thrombosis is related to atherosclerotic plaque. When plaque ruptures, it stimulates platelets to aggregate and form blood clots. The thrombus can block the blood vessel, or it can break off and travel with the blood, blocking smaller-diameter blood vessels. When it occurs in the brain, it is a cerebral infarction; when it occurs in the heart, it is a myocardial infarction. For the prevention of arterial thrombosis, it is necessary to use antiplatelet drugs such as aspirin, clopidogrel, and ticagrelor, which can inhibit the activity of platelets and avoid the formation of thrombosis. Carotid artery stenosis exceeding 50%, coronary heart disease, peripheral artery occlusion and other diseases related to arterial thrombosis require antiplatelet therapy.

Second, anticoagulation therapy

There are many activation factors in the coagulation process of the human body. In the venous system, the coagulation process is mainly induced by coagulation factors. Lower extremity surgery, trauma and keeping immobilized for a long time, or people who are bedridden and sedentary for a long time, may induce venous thrombosis in the lower extremity veins. After the venous thrombosis falls off, it will enter the pulmonary artery, causing pulmonary embolism and causing respiratory failure. If atrial fibrillation occurs, the blood returning from the pulmonary veins to the left atrium will also form a thrombus under the action of coagulation factors, and it is easy to block the cerebral arteries after falling off, causing cerebral infarction. For the prevention of venous thrombosis, it is necessary to use anticoagulation factor drugs such as warfarin and rivaroxaban to inhibit the activity of coagulation factors and avoid the formation of thrombosis.

Third, choose preventive drugs according to risk

The incidence of arterial thrombosis is higher, so in actual treatment, antiplatelet drugs are more commonly used. However, antiplatelet drugs can easily increase the risk of bleeding and cause damage to the mucosa of the digestive tract, so the risk should be assessed before taking the drug. In general, antiplatelet therapy is only used to prevent disease in people diagnosed with coronary heart disease and carotid artery stenosis of more than 50%, and for people who have experienced cerebral infarction and myocardial infarction to prevent recurrence. People who do not have the above diseases are not recommended to use the drug. Anticoagulant therapy increases the risk of bleeding and should only be administered to those at risk for atrial fibrillation and venous thrombosis. If there is a dual risk of arterial thrombosis and venous thrombosis at the same time, the two types of drugs can also be used at the same time. However, the bleeding risk will be superimposed, and medication needs to be carefully monitored.

IV. Lifestyle to prevent thrombosis

Arterial thrombosis and venous thrombosis occur in different systems and have different preventive medicines, but their pathological basis is similar. It is related to smoking, hypertension, diabetes, hyperlipidemia, obesity, aging, lack of exercise and other factors. To prevent disease, we must start from our lifestyle, not just rely on drugs. Every day, no more than 5 grams of salt, no more than 25 grams of oil, no more than 50 grams of added sugar, eat 1 catty of vegetables, half a catty of fruit, do aerobic exercise for more than 30 minutes, maintain a reasonable weight, and get enough sleep. Thrombotic disease can be avoided. Don't worry too much about the risk of disease. As long as you insist on rational drug use, you can minimize the risk of disease and still enjoy a happy life. To sum up, thrombosis in the human body, including arterial thrombosis and venous thrombosis, requires the use of antiplatelet therapy and anticoagulation therapy respectively in prevention. The medicine needs to be used under the guidance of a doctor. If you have any doubts about the medicine, please consult your doctor or pharmacist. I am Huazi, a pharmacist. Welcome to follow me and share more health knowledge.

(责任编辑:Anxiety disorder)

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