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What are the side effects of gout medicines? What do you need to pay attention to in your daily diet?

Time:2023-02-06 06:00:58 author:Mental disorder Read:216次
What are the side effects of gout medicines? What do you need to pay attention to in your daily diet?

Gout is caused by the deposition of uric acid crystals in the joint cavity of the body, and the onset is extremely painful. The causes are genetic factors and abnormal purine metabolism in the body. Purine metabolism produces uric acid. Hyperuricemia with a uric acid value exceeding 7.0 mg/dL will not only lead to Gout and urinary tract stones can also lead to high blood pressure and diabetes. Next, I will introduce three types of medicines for gout treatment. The first type can inhibit the infiltration of granulocytes, the accumulation of leukotriene inflammatory substances, and can be used for acute exacerbation of ventilation, colchicine, and the adverse reaction is urinary tract irritation, which hinders the absorption of vitamin B12 in the gastrointestinal tract and causes bone marrow suppression. Inhibited responses can be injected with vitamin B12. The second type can inhibit the production of xanthine oxidase and inhibit the production of uric acid. The representative drugs are allopurinol and febuxostat, which are used for gout patients in remission and renal insufficiency. patients with gout symptoms. The adverse reaction is exfoliative rash. The first use of this class of drugs will cause an increase in uric acid, because these drugs themselves are purines, so the increase in uric acid can be used in conjunction with colchicine. The third type can promote uric acid excretion and inhibit renal tubular reabsorption of uric acid. Probenecid and benzbromarone are used for the non-acute exacerbation of gout patients. The adverse reactions are skin rash and kidney stones. Children under 2 years old are contraindicated. Patients with high uric acid should pay attention to their usual diet, do not eat spicy food, do not drink beer, do not eat tofu, and foods containing more purines include beef, mutton, ham, animal offal, dried beans and their products, thick broth, chicken soup , fish soup, spinach, cauliflower, mushrooms, etc. Drink less soup and eat more meat, because 50% of purines are contained in soup.

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