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Why is Analgin being used less and less? How should children's antipyretics be used?

Time:2022-09-26 01:09:41 source:psychiatricethics.com author:Public activities Read:113次
Why is Analgin being used less and less? How should children's antipyretics be used?

#Exceptionalcase# A child's fever and headache is one of the most anxious things for parents and friends, especially if the high fever persists, parents and mothers will think of Analgin. Analgin is a combination of aminopyrine and sodium sulfite. From the 1980s to the beginning of this century, it has always been a leader in antipyretic and analgesic. Every child with fever will be sent to the clinic by a doctor. Analgin is a chlorpromazine injection, and children who do not want to be injected will also be given a few Analgin tablets, so that Analgin is a household name. When the children have a fever, parents and mothers will involuntarily think of a few tablets of Analgin: "Analgin is a good drug, cheap and effective, but unfortunately this cheap and good drug has no profit, and it is not good now. I bought it!" Little do I know that Analgin is gradually withdrawing from the market because it has serious side effects, the most important of which is agranulocytosis, which will reduce the body's immunity, suffer from viral or bacterial infection, and may also lead to coagulation disorders! Like Analgin, Xiao Chai Hu Injection, Aspirin, and Nimesulide are also banned in infants and young children. Let's take a look at the side effects of these drugs? So what other drugs can we use besides these few drugs? The main medicines used for antipyretics are ibuprofen and acetaminophen, which are relatively safe compared to the above medicines. However, parents and friends can't just take a few more tablets in order to reduce the fever and attack the heart, and the fever will subside quickly. These two drugs are metabolized in the liver. Since the detoxification ability of children's liver is not strong, when taking them Still have to take the amount! So how should it be used? For ibuprofen, the concentration of ibuprofen suspension is usually 20mg/ml, and the concentration of suspension drops is usually 40mg/ml. The dose of 5-10mg per kilogram of body weight is required, and the interval between two doses is not less than 4 hours, and no more than 4 times within 24 hours. A child about 1 year old weighs 10kg, and the maximum dose of ibuprofen should be 50-100mg each time. If it is a suspension, take 2.5~5ml at a time; if it is a suspension drop, take 1.25~2.5ml at a time. For acetaminophen, the concentration of acetaminophen suspension is usually 32 mg/ml, and the concentration of suspension drops is usually 40 mg/ml. A dose of 10-15 mg per kilogram of body weight should be taken, and the interval between two doses should not be less than 4 hours, and no more than 4 times within 24 hours. A child about 1 year old weighs 10kg, and the amount of acetaminophen should be 100-150mg each time. If it is a suspension, take 3~4.5ml at a time; if it is a suspension drop, take a maximum of 2.5~3.75ml at a time. Therefore, the gradual withdrawal of Analgin does not mean that the drug is cheaper and less profitable, and manufacturers are unwilling to produce it, but that there is a better and safer drug than Analgin. And be careful not to overdose on antipyretics!

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