Time：2023-03-26 01:18:27 source：psychiatricethics.com author：Mental disorder Read：515次

Schizophrenia drugs can not cure minimally invasive surgery into a new way for patients

Original article, misappropriation must be investigated. It is well known that when a patient with schizophrenia attacks, it will seriously affect their thinking, language, emotion and behavior, and interfere with their social activities and daily life. Social pressure is important. The most effective treatment strategies for schizophrenia include drug therapy, surgery, supplemented by psychological rehabilitation guidance, lifestyle changes, and social support. Among them, drugs for schizophrenia work by reducing psychiatric symptoms such as hallucinations, delusions, and thought disturbances, but have little effect on symptoms such as social withdrawal, lack of motivation, and lack of emotional expression. At the same time, schizophrenia requires long-term treatment. Even if patients feel better, they should take medication regularly to prevent the disease from recurring. As symptoms improve, some patients can reduce the dose or even stop the medication with the help of a doctor. Although the symptoms of most patients are relieved or improved after drug treatment, there are still some patients who take the drug regularly but have no effect, and the symptoms are repeated and aggravated. For such patients with refractory schizophrenia, since drugs cannot control their symptoms, surgery is their only treatment. Surgery can not only eliminate abnormal symptoms, but also help patients improve coping and life skills, manage stress, and solve Interpersonal problems and improve communication. The patient Xiao Liu is 23 years old this year. Six years ago, he suffered from poor sleep and low mood. He did not want to go to school. He said nonsense that his shoulders were high and the other was low. After a period of time, Xiao Liu became sensitive and suspicious. He suspected that someone was targeting him and talking about him behind his back. Schizophrenia", was hospitalized with amisulpride and other drugs, and was discharged after his condition improved. After being discharged from the hospital, Xiao Liu took the medicine according to the doctor's order, and his symptoms were not well controlled. He felt that life was meaningless and he didn't want to live. His behavior gradually became abnormal. He went out in the middle of the night with a kitchen knife and scissors. He washed his hands, looked in the mirror repeatedly, spoke to the mirror, and was hospitalized 4 times, but the effect was not significant, and the symptoms recurred many times. In the end, Xiao Liu, accompanied by his father, went to the functional neurology department of our hospital for surgical treatment. After the operation, Xiao Liu's original delusions, sensitive and suspicious, nonsense, strange behavior, and auditory hallucinations disappeared, and his thinking returned to normal. Gentle and restrained.

Why is long-term medication for schizophrenia unsatisfactory?

First of all, the pathogenesis of schizophrenia is not clear, and drug treatment is only symptomatic treatment, not for the cause; some drugs are not even symptomatic, and the natural effect is poor. Secondly, mental patients often have changes in brain nerve structure and transmitters; the longer the course of the disease, the more obvious this abnormal brain structure is, and conventional drug treatment often produces drug resistance, and the efficacy is not satisfactory. Moreover, antipsychotic drugs all have certain toxic and side effects, and patients overdose in pursuit of curative effects; Unlike drug treatment, which requires long-term metabolism, some patients cannot fully absorb the drug effect due to the barrier of the blood-brain barrier, but are metabolized out of the body, so drug treatment cannot fully play a role, but surgical treatment of schizophrenia is accurate through radiofrequency electrical stimulation. Regulate the emotional circuit area of ​​the brain, so as to obtain functional changes, and the effect can be seen after surgery.

To our readers:

Hello, I am Dr. Wu Jingwen, and I would like to thank you all for reading my article. If you have a disease and consult me, you can contact me through the platform "private message". You can also leave a message under the article, and I will answer your questions as soon as possible.

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(责任编辑：Leisure vacation)

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