Time：2023-03-26 00:46:50 source：psychiatricethics.com author：Relax Read：892次

How to deal with liver damage caused by drug therapy?

The 35-year-old Mr. Bai has suffered from depression for 6 years. He has been taking medication for 6 years. Through medication, his condition has been stably controlled, and he can basically lead a normal life. During this period, his attending doctor once reminded him that he can try to reduce the medication until it is stopped. . At that time, Mr. Bai was very happy and followed the doctor's instructions to gradually reduce the dose. However, as the concentration of the drug in the body decreased, Mr. Bai was always worried that the disease would recur, and was suffering in his heart. After communicating with the doctor, he decided to resume the dose. But the dose is smaller than the treatment dose. Moreover, the doctor reminded him to have a liver function test every six months, but Mr. Bai didn't take it seriously. He continued to take it for more than 2 years. Until the recent physical examination at the unit, the doctor told him that his liver function was abnormal and he had better go further. After inspection, Mr. Bai realized the problem and quickly made an appointment with a psychiatrist on the Enen Psychological APP for consultation. Before explaining whether antidepressants can affect liver function, let's take a look at how drugs are metabolized. After the drug is orally taken into the body by the human body, it is absorbed by the stomach and intestines, and the blood transports the drug to all parts of the human body, and then it is metabolized a little bit and excreted from the body. In order for a drug to work fully, it needs to be metabolized and transformed by the liver. This is like if you work 8 hours a day, suddenly it increases to 12 hours, you will definitely be physically and mentally exhausted and your body will be overwhelmed. As the saying goes, medicine is three-part poison. This poison is actually the side effect of medicine and the damage to the liver function of the body. Therefore, for chronic patients who need to take medicine for a long time, liver function tests should be carried out regularly. But don't be too nervous, refuse drug treatment, the harm of taking medicine is not so great: First, the human body has a strong self-repairing function, and most of the minor liver metabolism abnormalities caused by the drug can be self-recovered after the drug is stopped. Second: all the depressants purchased from regular channels on the market have been clinically tested and approved by the state, with side effects controlled within a certain range, with safety guarantees! So, will long-term use of antidepressants damage liver function? Depression is a psychiatric disease. In principle, if it is moderate or above, it needs drug treatment. If the disease is mild, the treatment will be as short as one and a half years. For those with severe disease, some take medicine for three to five years, while others may take medicine. Lifelong medication is required.

Which measures can be taken to protect the liver while taking antidepressants:

①Do a comprehensive physical examination before taking antidepressants to evaluate the health of the body Comprehensive conditions, especially liver function (liver function, kidney function) ② For the situation requiring long-term medication, it is recommended to use selective serotonin reuptake inhibitor drugs, such as sertraline, fluoxetine, paroxetine, chypre Peptide blue, fluvoxamine, etc., this type of drug has less effect on human liver from clinical feedback. ③ It is recommended to review it every six months, mainly to see if the transaminase is abnormal. If there is an impact, you can consider changing the dressing or using liver-protecting drugs if necessary. ④ For cases with relatively mild disease and obvious social and psychological factors in the cause of the disease, it is recommended to use psychotherapy. ⑤ Maintain a regular diet and work and rest habits, especially quit smoking and drinking, and eat less fried junk food in diet. ⑥ It is not allowed to change and adjust the medicine without permission, in order to prevent adverse reactions between the medicines and cause harm to the body. ⑦ Pay attention to your physical condition. If you have various physical discomforts such as liver discomfort, loss of appetite, nausea and vomiting, it is best to go to the hospital for examination and treatment! If you suspect that you have mental and psychological problems such as depression, anxiety, schizophrenia, social anxiety, etc., you can follow me and leave a private message if you have any questions, or you can take a self-assessment on the homepage. There are various professional scales on the homepage!

(责任编辑：Leisure vacation)

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